Cor et Vasa - Latest articles

Sto let od narození profesora Jiřího WidimskéhoPersonalities

Prof. MUDr. Jiří Widimský Jr., CSc.

Cor Vasa 2025, 67(2):307-309  

Filip Dosbaba, Ladislav Baťalík, Kateřina Filáková a kolektiv: Kardiovaskulární rehabilitace a prevenceBook reviews

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2025, 67(2):316  

Profesor Josef Veselka oslaví šedesáté narozeninyPersonalia

Michael Aschermann

Cor Vasa 2025, 67(2):315  

Ludmila Klímová slaví životní jubileumPersonalia

Michael Aschermann

Cor Vasa 2025, 67(2):314  

Významné jubileum paní profesorky CífkovéPersonalia

Michael Aschermann

Cor Vasa 2025, 67(2):312-313  

Opustila nás prof. MUDr. Lenka Špinarová, Ph.D., FESC (6. 8. 1961-11. 4. 2025)Personalities

Prof. MUDr. Jiří Vítovec, CSc.; prof. MUDr. Jan Krejčí, Ph.D.

Cor Vasa 2025, 67(2):310-311  

Myocardial infarction in a young patient with antiphospholipid syndrome: A case reportCase reports

Marta Catarina Bernardo, Catarina Ribeiro Carvalho, Catarina Ferreira, Inês Silveira, Ana Batista, Sofia Silva Carvalho, Ilídio Moreira

Cor Vasa 2025, 67(2):302-304 | DOI: 10.33678/cor.2024.085  

This case report highlights the importance of a multimodal approach, tailored therapeutic interven- tions, and the poor prognosis of myocardial infarction with non-obstructive coronary arteries (MINOCA) in a young patient with antiphospholipid syndrome (APS). A 39-year-old man was admitted with a diagnosis of a ST elevation myocardial infarction (STEMI), in Killip class III. Angiography showed absence of obstructive epicardial coronary artery disease prompting further evaluation with cardiac magnetic resonance imaging (MRI). It revealed infarction scars in multiple arterial territories and severe left ventricular dysfunction. The patient evolved with...

(Current treatment options of pulmonary arterial hypertension in the Czech Republic, its limitations and perspectives, update of the therapeutic algorithm for pulmonary arterial hypertension. Expert consensus statement of the Working Group on Pulmonary Circulation of the Czech Society of Cardiology)Expert consensus statement

Pavel Jansa, David Ambrož, Marián Felšőci, Lucie Miksová, Jan Přeček, Hikmet Al-Hiti, Radek Pudil, Martin Hutyra

Cor Vasa 2025, 67(2):295-300 | DOI: 10.33678/cor.2025.046  

Pulmonary hypertension is defined as a syndrome characterized by an increase of the mean pulmonary artery pressure >20 mmHg. Pulmonary arterial hypertension (PAH) is a rare disease that accounts for approximately 1% of all cases of chronic pulmonary hypertension. In the pathophysiology, the key factor is initially vasoconstriction, followed by remodeling of pulmonary arterioles, accompanied by an increase of pulmonary vascular resistance and the right ventricle chronic pressure overload. In the treatment of PAH, medical therapy is dominant. Patients with a positive vasoreactivity testing are indicated for treatment with high doses of calcium channel...

2024 ESC Guidelines for the management of chronic coronary syndromes (Translation of the shortened document prepared by the Czech Interventional Cardiology Association of the Czech Society of Cardiology)Guidelines

Petr Kala, Radek Pudil, Ivo Varvařovský, Hana Skalická, Vrints C, Andreotti F, Koskinas KC, Rossello X, Adamo M, Ainslie J, Banning AP, Budaj A, Buechel RR, Chiariello GA, Chieffo A, Christodorescu RM, Deaton C, Doenst T, Jones HW, Kunadian V, Mehilli J, Milojevic M, Piek JJ, Pugliese F, Rubboli A, Semb AG, Senior R, ten Berg JM, Van Belle E, Van Craenenbroeck EM, Vidal-Perez R, Winther S

Cor Vasa 2025, 67(2):230-294 | DOI: 10.33678/cor.2025.052  

2024 ESC Guidelines for the management of peripheral arterial and aortic diseases (Translation of the shortened document prepared by the Czech Society of Cardiology)Guidelines

Pavel Procházka, Petr Vařejka, Jiří Matuška, Mazzolai L, Teixido-Tura G, Lanzi S, Boc V, Bossone E, Brodmann M, Bura-Rivière A, De Backer J, Deglise S, Della Corte A, Heiss C, Kałużna-Oleksy M, Kurpas D, McEniery CM, Mirault T, Pasquet AA, Pitcher A, Schaubroeck HAI, Schlager O, Sirnes PA, Sprynger MG, Stabile E, Steinbach F, Thielmann M, van Kimmenade RRJ, Venermo M, Rodriguez-Palomares JF

Cor Vasa 2025, 67(2):182-229 | DOI: 10.33678/cor.2025.051  

2024 ESC Guidelines for the management of peripheral arterial and aortic diseases (Translation of the summary of the document prepared by the Czech Society of Angiology, 2025)Guidelines

Debora Karetová, Miroslav Chochola, Jana Hirmerová, Jiří Matuška, Jan Piťha, Mazzolai L, Teixido-Tura G, Lanzi S, Boc V, Bossone E, Brodmann M, Bura-Rivière A, De Backer J, Deglise S, Della Corte A, Heiss C, Kałużna-Oleksy M, Kurpas D, McEniery CM, Mirault T, Pasquet AA, Pitcher A, Schaubroeck HAI, Schlager O, Sirnes PA, Sprynger MG, Stabile E, Steinbach F, Thielmann M, van Kimmenade RRJ, Venermo M, Rodriguez-Palomares JF

Cor Vasa 2025, 67(2):135-181 | DOI: 10.33678/cor.2025.050  

2024 ESC Guidelines for the management of atrial fibrillation (Translation of the shortened document prepared by the Czech Heart Rhythm Association of the Czech Society of Cardiology)Guidelines

Lucie Šedivá, Robert Čihák, Štěpán Havránek, Martin Fiala, Van Gelder IC, Rienstra M, Bunting KV, Casado-Arroyo R, Caso V, Crijns HJGM, De Potter TJR, Dwight J, Guasti L, Hanke T, Jaarsma T, Lettino M, Løchen ML, Lumbers RT, Maesen B, Mølgaard I, Rosano GMC, Sanders P, Schnabel RB, Suwalski P, Svennberg E, Tamargo J, Tica O, Traykov V, Tzeis S, Kotecha D

Cor Vasa 2025, 67(2):95-134 | DOI: 10.33678/cor.2025.041  

Radek Ptáček, Petr Bartůněk (editoři): Bolest v medicíněKardio

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2025, 67(1):88  

Zemřel prof. MUDr. Jiří Fodor, CSc., FRCPC, FAHA (28. 10. 1927–10. 12. 2024)Personalities

Prof. MUDr. Renata Cífková, CSc.

Cor Vasa 2025, 67(1):87  

Centra sportovní kardiologie: odborné stanoviskoKardio

Vladimír Tuka, Bogna Jiravská Godula, Otakar Jiravský, Peter Kubuš, Eliška Sovová

Cor Vasa 2025, 67(1):85-86  

Centra sportovní kardiologieKardio

Vladimír Tuka, Bogna Jiravská Godula, Otakar Jiravský,, Peter Kubuš, Eliška Sovová

Cor Vasa 2025, 67(1):83-84  

High-Sensitivity Cardiac Troponin T Elevation and Paroxysmal Supraventricular Tachycardia. Is it Always Acute Coronary Syndrome?Case reports

Serena Miccichè, Giuseppe Pelaggi, Maria Claudia Lo Nigro, Simone Celeste, Alice Moncada, Olga La Cognata, Armando Lo Savio, Salvatore Bonanno, Paolo Bellocchi, Graziella Agnelli, Alessio Currò

Cor Vasa 2025, 67(1):77-81 | DOI: 10.33678/cor.2024.063  

Background: Paroxysmal supraventricular tachycardia (PSVT) is a common arrhythmia often presenting with symptoms mimicking acute coronary syndrome (ACS). Case presentation: We present a case of a 58-year-old man with PSVT accompanied by chest pain and elevated high-sensitivity troponin (hs-Tn) levels. Coronary angiography revealed slow coronary flow in absence of obstructive disease. The patient's symptoms resolved spontaneously, and echocardiographic findings normalized upon discharge. Conclusions: This case underscores the diagnostic challenge of individuating ACS and highlights the transient troponin elevation seen in PSVT, potentially due to myocardial...

The Role of Oral Calcium and Vitamin D in Hypocalcemia-Associated Cardiomyopathy: A Case ReportCase reports

Meity Ardiana, Bambang Herwanto, Inna Maya Sufiyah, Wynne Widiarti, Alviannur Halim

Cor Vasa 2025, 67(1):73-76 | DOI: 10.33678/cor.2024.058  

Hypocalcemia-associated cardiomyopathy, a rare but serious condition, presents challenges in diagnosis and management. Severe hypocalcemia resulting from hypoparathyroidism can precipitate rare yet reversible cases of dilated cardiomyopathy. This case report reported a 31-year-old woman with heart failure precipitated by hypoparathyroidism following thyroidectomy. Despite conventional heart failure treatments, her condition persisted until correction of hypocalcemia. Treatment involved calcium supplementation and guideline-directed heart failure therapy. Significant improvement was observed then. Hence, monitoring serum calcium levels is imperative...

(Rare rhythm disorder in patients with hypertrophic obstructive cardiomyopathy during endocardial radiofrequency ablation of septal hypertrophy)Case reports

Katarína Doležalová, Zdeněk Stárek, Tomáš Honek, Filip Souček, Martin Pešl, Jan Krejčí

Cor Vasa 2025, 67(1):67-72 | DOI: 10.33678/cor.2024.108  

Hypertrophic obstructive cardiomyopathy (HOCMP) is characterized by abnormal thickening or enlargement of the left ventricular myocardium mass of non-dilated left ventricle not explained solely by loading conditions and presence of obstruction in outflow tract of left ventricle. Surgical septal myectomy was the first choice method of invasive treatment of septal hypertrophy in the past which was replaced by alcohol septal ablation in the nineties of the 20th century and nowadays it is still worldwide used, safe, and effective method in reduction of septal hypertrophy. Nowadays there is a new method of non-pharmacological treatment of septal hypertrophy...

Persistent Severe Bradyarrhythmia Following Donepezil Discontinuation in Dementia Patient: A Case Report and Literature ReviewReview articles

Okky Wahyu Firmansyah, Budi Baktijasa Dharmadjati, Rerdin Julario, Chabib Fachry Albab, Pandit Bagus Tri Saputra, Emil Prabowo

Cor Vasa 2025, 67(1):60-65 | DOI: 10.33678/cor.2024.060  

Background: Donepezil is an acetylcholinesterase inhibitor used in Alzheimer's disease management. It improves clinical symptoms but carries risks of orthostatic hypotension and bradycardia. Uncommon severe bradyarrhythmias post-discontinuation deserve attention. In addition, there have been no previous case reports regarding severe bradyarrhythmias post donepezil discontinuation. Case presentation: We report a case of a 33-year-old woman with a history of recurrent fainting. She has dementia and regularly takes donepezil. She experienced severe bradyarrhythmia with heart rate of 45 beats per minute regular on dopamine 5 µg/kg/min and unresponsive...

Minimally Invasive Management of Cystic Adventitial Disease in the Popliteal Artery: A Case Report and ReviewReview articles

Alexander Daskalov, Boris Ilchev

Cor Vasa 2025, 67(1):56-59 | DOI: 10.33678/cor.2025.011  

Background: Cystic adventitial disease (CAD) is a rare cause of arterial stenosis, primarily affecting the popliteal artery. Case presentation: A 46-year-old male presented with sudden right calf pain. Physical examination and CT angiography revealed significant stenosis of the right popliteal artery. Initial thrombectomy failed to remove thrombotic material, prompting a hybrid approach with PTA and stent implantation. MRI confirmed CAD, and the patient remained asymptomatic at 24-month follow-up. Discussion: The etiology of CAD is debated, with theories including local trauma and synovial/ganglion origin. Traditional management has been surgical,...

Spontaneous Coronary Artery Dissection in Patients with COVID-19: A Systematic Review of Published Case ReportsReview articles

Andrianto, Chabib F. Albab, Nabila R. Putri, Pratista Oktafia, Roy B. Kurniawan

Cor Vasa 2025, 67(1):48-55 | DOI: 10.33678/cor.2024.081  

Background: Spontaneous coronary artery dissection (SCAD) presents a unique challenge due to its prompt diagnosis and treatment requirements, demanding an in-depth understanding of its underlying mechanisms. This systematic review aims to provide a comprehensive summary of the SCAD cases in patients diagnosed with COVID-19. Methods: We performed a systematic search across databases, including PubMed, ScienceDirect, and Cochrane, on June 3, 2023. We included reported cases of SCAD in COVID-19 patients that described individual patient data. Results: The study analyzed 12 case reports, revealing that all patients were confirmed COVID-19 cases with a...

(Detection and treatment of arrhythmias in patients with transthyretin cardiac amyloidosis)Review articles

Ivona Šimková, Renáta Aiglová, Enikö Marczibál, Marián Fedorco, Miloš Táborský

Cor Vasa 2025, 67(1):43-47 | DOI: 10.33678/cor.2024.099  

Arrhythmias are a very common manifestation of transthyretin cardiac amyloidosis. The review article focuses on the mechanisms that lead to the development of atrial fibrillation, cardiac conduction disorders, and ventricular arrhythmias, as well as their incidence and prevalence. It emphasizes the possibilities of using external and implantable monitoring devices in the detection of arrhythmias. It summarizes modern therapeutic approaches with particular attention to radiofrequency catheter ablation and the use of direct oral anticoagulants in atrial fibrillation and flutter. It mentions the challenges of cardiac pacing and prevention of sudden cardiac...

(Continuous thermodilution - a novel method for direct measurement of coronary flow and resistance)Review articles

Petr Kala, Radka Adlová, Veronika Gašpárková, Petr Ošťádal, Petr Hájek

Cor Vasa 2025, 67(1):35-42 | DOI: 10.33678/cor.2024.101  

Angina with non-obstructive coronary artery disease is a frequent finding in patients with chest pain. Its pathophysiology involves two main mechanisms: structural and functional dysfunction of microcircula- tion, functional dysfunction of epicardial arteries, and their combination. The review article focuses on the diagnostics of microvascular dysfunction, particularly continuous thermodilution, as a safe, easy, fast, and operator-independent method. It describes both theoretical background and practical aspects with graphical examples of measurements.

Thyroid Doppler parameters association with coronary atherosclerosis burdenOriginal research articles

Ali AlQazzaz, Wasan Kadhum Abbas, Hussein Nafakhi, Abdulameer A. Al-Mosawi, Hayder Nafakhi

Cor Vasa 2025, 67(1):30-34 | DOI: 10.33678/cor.2024.097  

Background: Little is known about the potential association between thyroid vascular parameters and coronary atherosclerotic burden in patients with suspected coronary artery disease. Objectives: To assess the potential association between superior thyroid artery Doppler parameters and coronary atherosclerotic markers, including stenosis severity, coronary artery calcification (CAC), and plaque assessed by multi-detector CT (MDCT) coronary angiography among patients with suspected coronary artery disease (CAD). Patients and methods: This cross-sectional study included 100 patients with chest pain who underwent MDCT coronary angiography to exclude the...

The prognostic importance of the percentage of immature granulocyte in 28-day mortality in patients with acute coronary syndromeOriginal research articles

Cihan Can, Hüseyin Narci, Akif Yarkaç, Özcan Örsçelik, Cüneyt Ayrik

Cor Vasa 2025, 67(1):24-29 | DOI: 10.33678/cor.2025.009  

Background: The percentage of immature granulocytes (IG%) is an early marker of inflammation and has a prognostic significance in many diseases. Objective: In this study, we tried to investigate whether the percentage of immature granulocytes has a prognostic value in 28-day mortality in patients with acute coronary syndrome (ACS). Method: This study was carried out retrospectively between 1.1.2019 and 30.6.2019 at Mersin University Faculty of Medicine, Department of Emergency Medicine. Patients older than 18 years who applied to the emergency department with chest pain and were hospitalized with a preliminary diagnosis of ACS were included in the...

18-Year Outcomes of Aortic Leaflet Extension Valvuloplasty Using Autologous Pericardium and Polytetrafluoroethylene: Single-Centre, Propensity-Matched AnalysisOriginal research articles

Matej Nosáľ, Fadi Sabateen, Pavel Valentík, Michal Šagát, Aref Saif Nagi, Kristína Kasičová, Vladimír Soják

Cor Vasa 2025, 67(1):16-23 | DOI: 10.33678/cor.2024.105  

Background: Aortic valve repair with leaflet extension is routinely utilized in the management of aortic valve disease in children and adolescents. The material chosen may have an effect on the valve function and durability. Aims: To evaluate long-term outcomes of aortic valve repair using autologous pericardium and polytetrafluoroethylene (PTFE) leaflet extensions and to investigate risk factors for aortic valve reoperation at single centre. Methods: A retrospective single-centre review of 89 patients undergoing aortic valvuloplasty by leaflet extensions with either autologous pericardium or PTFE from 2005 to 2023. Results: Eighty-nine patients (75%...

Near-infrared spectroscopy derived indexes as a potential predictor of plaque burden volume progression after unprotected left main coronary artery interventionOriginal research articles

Martin Hudec, Jan Kaňovský, Vojtěch Brázdil, Martin Poloczek, Ivona Kask, Kristýna Hochmanová, Radka Smitalová, Otakar Boček, Petr Jeřábek, Roman Štípal, Simona Littnerová, Jiří Jarkovský, Klára Benešová, Petr Kala

Cor Vasa 2025, 67(1):6-15 | DOI: 10.33678/cor.2025.010  

Background: Coronary artery disease (CAD) is the leading cause of death worldwide, which has driven significant advances in the field of interventional cardiology. The combination of intravascular ultrasound (IVUS) and near-infrared light spectroscopy (NIRS) offers a detailed view of coronary artery morphology and plaque composition. This advanced imaging capability facilitates a more accurate assessment of CAD and enhances therapeutic strategies. Objective: NIRS can detect and quantify lipid content in atherosclerotic plaque using the Lipid Core Burden Index (LCBI) and the Maximal Lipid Core Burden Index in a 4 mm segment (maxLCBI4mm). In this study,...

Congress abstracts: Czech Cardiovascular Research and Innovation Days 2024Abstracts

editorial staff

Cor Vasa 2024, 66(Suppl. 2):4-48  

Vienna House Hotel, Prague, November 4–5, 2024

Congress abstracts: ECPR Prague School, Cubex Centrum Prague, October 24–26, 2024Abstracts

editorial staff

Cor Vasa 2024, 66(Suppl. 1):4-14