Sinus of Valsalva aneurysm - myocardial infarction perpetrator or silent bystander?Case reports

Martin Jedlička, Michal Fikrle, Roman Panovský, Lucia Masárová

Cor Vasa 2024, 66(3):366-369 | DOI: 10.33678/cor.2023.074  

Background: In some cases myocardial infarction is not associated with atherothrombotic coronary artery dis- ease and can be caused by many different mechanisms. One of these situations is a coronary artery embolism. This case report discusses the possibility of coronary embolism from newly diagnosed sinus of Valsalva aneurysm (SOVA), which is a rare clinical abnormality that can be clinically silent or symptomatic in varied ways. Case presentation: A 54-year-old woman presented with ST-segment elevations myocardial infarction of left ventricle inferior wall. We performed emergent coronary angiography where occlusion of the posterior descending artery...

(Traditional risk factors and chronic diseases associated with an increased risk of coronary artery disease. Risk stratification and intervention from childhood)Review articles

Veronika Urbanová, Jakub Mrakava, Karel Koubský, Irena Aldhoon-Hainerová, Kristina Rücklová

Cor Vasa 2024, 66(3):349-364 | DOI: 10.33678/cor.2023.100  

Coronary artery disease risk not only in adults but also in children is predominantly related to risk factors associated with atherosclerosis. These traditional cardiovascular risk factors include hypercholesterolaemia, obesity, diabetes mellitus, hypertension and smoking. Another high risk group for coronary artery disease are individuals with cardiac, vascular or other chronic diseases. These include chronic kidney diseases, chronic inflammatory diseases, malignancies, certain congenital heart defects, inborn or acquired coronary anomalies including interventions on coronary arteries, Kawasaki disease and cardiac allograft vasculopathy in heart transplant...

(Ambulatory blood pressure monitoring, sleep quality, and reliability of night hypertension)Review articles

Samuel Genzor, Eva Kociánová, Ladislav Stanke, Michal Štýbnar, Jan Mizera, Martin Vykopal

Cor Vasa 2024, 66(3):345-348 | DOI: 10.33678/cor.2023.087  

Nocturnal hypertension is a significant risk factor for cardiovascular mortality and morbidity. Its determination requires the use of 24-hour blood pressure monitoring (ABPM). However, the examination results can be less reliable in patients with insomnia, habitual short sleep or other sleep disorders. In these patients, it is possible to detect falsely high values of blood pressure in the night interval. At the same time, the treatment of sleep disorders itself could adjust the nighttime values of blood pressure and thus prevent unreasonably intensive treatment of high blood pressure. The article summarizes current knowledge about the effect of sleep...

(The inferior vena cava filter and complications associated with its use)Review articles

Marek Hudák, Martin Koščo, Lucia Dekanová, Veronika Pavlíková, Eva Szabóová, Mária Rašiová

Cor Vasa 2024, 66(3):335-343 | DOI: 10.33678/cor.2024.015  

The inferior vena cava filter prevents pulmonary embolism by mechanically trapping the embolus in the inferior vena cava. It should be strictly indicated and implanted only in a selected group of patients with deep vein thrombosis. However, the introduction of a plenty relative indications significantly increased the rate of caval filter implantation in the last decade and it led consequently to dramatic increase of complications rate, too. The purpose of this article is to summarize the possible complications related to the use of the caval filter, to present the reader clinical manifestation of these complications, as they are often overlooked, and...

The role of neutrophil-to-lymphocyte ratio in left ventricular hypertrophy development in patients with comorbid course of hypertension, diabetes mellitus, and obesityOriginal research articles

Oleksandra Babycheva, Olga Sadovenko, Iulia Rodionova, Inna Kutia, Anton Bilchenko, Borys Shelest, Nataliia Sukhonos, Yuliia Kovalova

Cor Vasa 2024, 66(3):328-334 | DOI: 10.33678/cor.2024.008  

Objective: The patients with concurrent hypertension, diabetes mellitus (DM), and obesity are among the most common associated conditions in contemporary clinical practice. It is of crucial importance to investigate the development of left ventricular hypertrophy (LVH) in above mentioned complicated comorbid patients. The association of neutrophil-to-lymphocyte ratio (NLR) with the development of LVH is not researched enough. The aim of the work was to study the role of NLR in the development of LVH in hypertensive patients burdened with type 2 diabetes and obesity. Methods: 297 hypertensive patients with diabetes mellitus type 2 and obesity were enrolled...

Early-LVT Risk Score - A new Clinical Risk Score for Early Left Ventricular Thrombus Prediction Following AnteriorST-Segment Elevation Myocardial InfarctionOriginal research articles

Joana Laranjeira Correia, Vanda Devesa Neto, João Gouveia Fiuza, Luísa Gonçalves

Cor Vasa 2024, 66(3):323-327 | DOI: 10.33678/cor.2024.004  

Background: Despite advancements in the management of ST-segment elevation myocardial infarction (STEMI), the risk of left ventricular thrombus (LVT) remains a significant concern due to its potential for embolic complications. Early identification of patients at high risk for LVT is crucial for guiding therapeutic interventions and improving clinical outcomes. Aim: This study aimed to develop a practical and clinically applicable risk score (Early-LVT Risk Score) that integrates readily available demographic, clinical, and echocardiographic parameters to predict the likelihood of early LVT formation post anterior STEMI. Methods: A sub-analysis of...

Cancer Diagnosis in Hypertensive Heart Disease Population: A Cross Sectional Study in Soetomo General HospitalOriginal research articles

Meity Ardiana, Wynne Widiarti, Chaq El Chaq Z. Multazam, Hanif Ardiansyah Sulistya

Cor Vasa 2024, 66(3):318-322 | DOI: 10.33678/cor.2024.003  

Hypertension as a global concern remains inadequately controlled, ultimately leading to cardiac structural and functional changes associated with hypertensive heart disease (HHD). Simultaneously, cancer, characterized with abnormal cell proliferation, exhibits diverse behaviours and responses to treatment strategies. Despite extensive efforts, certain type of cancers remains incurable, making both cardiovascular diseases and cancer the leading causes of non-communicable disease mortality in the world. To investigate this association, we conducted a cross-sectional study, reporting the incidence of cancer in the HHD population at Soetomo General Hospital....

Prognostic importance of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score in patients with acute pulmonary embolismOriginal research articles

Ekrem Taha Sert, Kamil Kokulu, Hüseyin Mutlu, Mustafa Önder Gönen

Cor Vasa 2024, 66(3):312-317 | DOI: 10.33678/cor.2023.099  

Objective: To investigate the prognostic value of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score in acute pulmonary embolism (APE). Methods: We retrospectively evaluated patients aged 18 years and over who were diagnosed with APE by computed tomography pulmonary angiography at the emergency department (ED) between January 2019 and January 2023. The patients' clinical and demographic data were evaluated, and their simplified pulmonary embolism severity index values were calculated. The HALP score was obtained using the first blood sample measured after the patients were admitted to the ED. The HALP score was calculated according to the...

Predictors of major adverse cardiovascular events in patients with coronary artery perforation treated with covered stentsOriginal research articles

Umeyir Savur, Aysel Akhundova, Başak Çatalbaş, İbrahim Oguz Karaca

Cor Vasa 2024, 66(3):307-311 | DOI: 10.33678/cor.2024.002  

Background: Coronary artery perforation (CAP) is a rare, life-threatening complication of percutaneous coronary intervention (PCI). PTFE-coated stents are highly successful and lifesaving in the treatment of coronary perforation. The incidence of thrombosis and restenosis in the PTFE-covered stent is higher than in standard stents. The aim of this study was to evaluate the clinical outcomes of PTFE-covered stents for CAP. Materials and methods: We evaluated a total of 38 patients who were treated with PTFE-coated stents for coronary perforation from January 2012 to January 2022 at a single high-volume center, Medipol University Hospital in Turkey....

(Mid-term results of dynamic aortic root remodeling - a single center study)Original research articles

Adrián Kolesár, Tomáš Toporcer, Tomáš Molnár, Lukáš Vajda, Martina Polačková, Jana Jevčáková, Lucia Mistríková, Štefánia Mižáková, Štefan Lukačin

Cor Vasa 2024, 66(3):302-306 | DOI: 10.33678/cor.2024.021  

Aortic root remodeling was first published in the 1980s. Today's aortic root remodeling is geometrically precisely defined and indicated in every patient with aortic valve regurgitation in aortic root aneurysm. The aim of the work is to evaluate the medium-term results of aortic root remodeling in our conditions and the risk factors that have an impact on this stability. The work included 103 patients undergoing aortic root remodeling from January 2011 to December 2013. Patient follow-up was performed by echocardiographic control in correlation with the recommendations of the international AVIATOR registry. The analysis of patient survival focused...

Jiří Bonaventura: Současná kardiologie. Manuál pro praxiBook reviews

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2024, 66(2):296  

Profesor MUDr. Aleš Linhart, DrSc., FESC, FCMA, slaví životní jubileumPersonalia

Michael Aschermann

Cor Vasa 2024, 66(2):295  

Prof. MUDr. Petr Widimský, DrSc., FESC, FACC, sedmdesátiletýPersonalia

Pavel Gregor

Cor Vasa 2024, 66(2):291-293  

Profesor Petr Widimský slaví životní jubileumPersonalia

Michael Aschermann

Cor Vasa 2024, 66(2):294  

Aktualizace Doporučení ESC pro diagnostiku a léčbu akutního a chronického srdečního selhání 2021. Vypracovaná Pracovní skupinou pro diagnostiku a léčbu akutního a chronického srdečního selhání Evropské kardiologické společnosti (ESC). Se zvláštním přispěním Evropské asociace srdečního selhání ESC.Guidelines

McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O, Cleland JGF, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M, Lam CSP, Lyon AR, McMurray JJV, Mebazaa A, Mindham R, Muneretto C, Piepoli MF, Price S, Rosano GMC, Ruschitzka F, Skibelund AK, McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O, Cleland JGF, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M, Lam CSP, Lyon AR, McMurray JJV, Mebazaa A, Mindham R, Muneretto C, Piepoli MF, Price S, Rosano GMC, Ruschitzka F, Skibelund AK, Jan Krejčí, Lenka Špinarová, Jiří Pařenica, Anna Chaloupka, Jiří Veselý

Cor Vasa 2024, 66(2):280-288 | DOI: 10.33678/cor.2024.018  

Doporučený postup Evropské kardiologické společnosti pro léčbu kardiovaskulárních onemocnění u pacientů s diabetem 2023.Guidelines

Marx N, Federici M, Schütt K, Müller-Wieland D, Ajjan RA, Antunes MJ, Christodorescu RM, Crawford C, Di Angelantonio E, Eliasson B, Espinola-Klein C, Fauchier L, Halle M, Herrington WG, Kautzky-Willer A, Lambrinou E, Lesiak M, Lettino M, McGuire DK, Mullens W, Rocca B, Sattar N, Marx N, Federici M, Schütt K, Müller-Wieland D, Ajjan RA, Antunes MJ, Christodorescu RM, Crawford C, Di Angelantonio E, Eliasson B, Espinola-Klein C, Fauchier L, Halle M, Herrington WG, Kautzky-Willer A, Lambrinou E, Lesiak M, Lettino M, McGuire DK, Mullens W, Rocca B, Sattar N, Michal Vrablík, Hana Rosolová, Miloš Táborský

Cor Vasa 2024, 66(2):233-279 | DOI: 10.33678/cor.2024.031  

Doporučení ESC pro léčbu akutních koronárních syndromů 2023.Guidelines

Byrne RA, Rossello X, Coughlan JJ, Barbato E, Berry C, Chieffo A, Claeys MJ, Dan GA, Dweck MR, Galbraith M, Gilard M, Hinterbuchner L, Jankowska EA, Jüni P, Kimura T, Kunadian V, Leosdottir M, Lorusso R, Pedretti RFE, Rigopoulos AG, Rubini Gimenez M, Thiele H, Vranckx P, Wassmann S, Wenger NK, Ibanez B, Byrne RA, Rossello X, Coughlan JJ, Barbato E, Berry C, Chieffo A, Claeys MJ, Dan GA, Dweck MR, Galbraith M, Gilard M, Hinterbuchner L, Jankowska EA, Jüni P, Kimura T, Kunadian V, Leosdottir M, Lorusso R, Pedretti RFE, Rigopoulos AG, Rubini Gimenez M, Thiele H, Vranckx P, Wassmann S, Wenger NK, Ibanez B, Petr Kala, Petr Ošťádal, Zuzana Moťovská, Martin Mates, Dagmar Vondráková, Jan Bělohlávek, Petr Fila, Ivo Varvařovský

Cor Vasa 2024, 66(2):169-232 | DOI: 10.33678/cor.2024.029  

Doporučený postup Evropské kardiologické společnosti pro léčbu endokarditidy 2023.Guidelines

Delgado V, Ajmone Marsan N, de Waha S, Bonaros N, Brida M, Burri H, Caselli S, Doenst T, Ederhy S, Erba PA, Foldager D, Fosbøl EL, Kovac J, Mestres CA, Miller OI, Miro JM, Pazdernik M, Pizzi MN, Quintana E, Rasmussen TB, Ristić AD, Rodés-Cabau J, Sionis A, Zühlke LJ, Borger MA, Delgado V, Ajmone Marsan N, de Waha S, Bonaros N, Brida M, Burri H, Caselli S, Doenst T, Ederhy S, Erba PA, Foldager D, Fosbøl EL, Kovac J, Mestres CA, Miller OI, Miro JM, Pazdernik M, Pizzi MN, Quintana E, Rasmussen TB, Ristić AD, Rodés-Cabau J, Sionis A, Zühlke LJ, Borger MA, Hana Línková, Dan Marek, Martin Mates, Jiří Beneš, Aleš Mokráček, Jana Rubáčková Popelová, Jan Janoušek, Tomáš Paleček, Michal Pazderník, Tomáš Zatočil

Cor Vasa 2024, 66(2):112-168 | DOI: 10.33678/cor.2024.017  

(Focused on heart failure treatment according to the updated 2023 guidelines)Review articles

Jaroslav Brotánek

Cor Vasa 2024, 66(2):105-111 | DOI: 10.33678/cor.2024.025  

Acute and chronic heart failure remains a very serious and high priority problem in contemporary cardiology. New, modern drugs are currently emerging in the treatment of heart failure while the possibilities of their further use for this diagnosis are being expanded. These findings have been summarized in the 2023 update of the European Society of Cardiology Guidelines for heart failure. This article provides a brief summary of the new developments in pharmacotherapy based on the above recommendations.

(Fixed combination and adherence in patients with recent myocardial infarction or manifest cardiovascular disease - our experience from the SECURE trial)Original research articles

Jean-Claude Lubanda, Hana Lubanda

Cor Vasa 2024, 66(2):99-102 | DOI: 10.33678/cor.2024.022  

A lack of adherence is associated with a worse prognosis. Decreasing adherence in post-MI patients leads to an increased risk of recurrence of ischemic events. In addition, due to the aging population and improved quality care for ACS with better survival, there is an increase in the number of patients who need more personalized secondary preventive interventions. For these patients, improving adherence is another way to improve their prognosis. The latest research shows that combination therapy, preferably in a fixed combination, should improve patient adherence and reduce the risk of CV disease complications. Thanks to the reduction in the number...

Petra Hátlová, Roman Šmucler a Štěpán Svačina: Debaty bez cenzury 3Book reviews

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2024, 66(1):91 | DOI: 10.33678/cor.2024.007  

Martin Polák: Urgentní příjem. Nejčastější znaky, příznaky a nemoci na oddělení urgentního příjmu. 3., přepracované a doplněné vydáníBook reviews

Prof. MUDr. Jan Petrášek, DrSc.

Cor Vasa 2024, 66(1):92 | DOI: 10.33678/cor.2024.013  

Za prof. MUDr. Ivanem Vaňkem, DrSc. (26. 6. 1942–8. 12. 2023)Personalities

Prof. MUDr. Josef Veselka, CSc.

Cor Vasa 2024, 66(1):90 | DOI: 10.33678/cor.2024.010  

Zemřel pan profesor MUDr. Ivan Vaněk, DrSc.Personalities

prof. MUDr. Jaroslav Lindner, CSc., FICS

Cor Vasa 2024, 66(1):89 | DOI: 10.33678/cor.2024.006  

(Commentary to the article The year in cardiovascular medicine 2022: the top 10 papers in heart failure and cardiomyopathies)Commentary

Filip Málek

Cor Vasa 2024, 66(1):87 | DOI: 10.33678/cor.2023.040  

Non-conducted premature atrial complexes: a silent culprit of atrial fibrillation onsetCase reports

Armando Lo Savio, Giampaolo Vetta, Antonio Parlavecchio, Rodolfo Caminiti, Michele Magnocavallo, Lorenzo Pistelli, Olga Mariarita La Cognata, Domenico Giovanni Della Rocca, Gianluca Di Bella, Pasquale Crea

Cor Vasa 2024, 66(1):84-86 | DOI: 10.33678/cor.2024.001  

Atrial fibrillation (AF) is the most common cardiac arrhythmia in adults with substantial morbidity and mortality. AF increases the risk of stroke 5-fold compared to the general population and oral anticoagulant therapy represents the cornerstone for stroke prevention. Therefore, it is necessary to identify predictive factors for the onset of AF in order to screen patients with a high probability of AF development. We report the case of a 69-year-old patient asymptomatic for palpitation with a 24-hour Holter ECG showing several ncPACs (non-conducted premature atrial complexes) leading to AF onset.

Differentiating between Exercise-Induced ST-Segment Abnormalities Secondary to Wolff-Parkinson-White (WPW) Syndrome and Acute Myocardial InfarctionCase reports

Meity Ardiana, Putu Dwipa Krisna Devi, Ryan Enast Intan, Inna Maya Sufiyah

Cor Vasa 2024, 66(1):80-83 | DOI: 10.33678/cor.2023.081  

Background: Exercise stress testing (EST) can cause false-positive diagnoses of myocardial infarction (MI) in individuals with Wolff-Parkinson-White (WPW) syndrome. Case: A 30-year-old male had a history of palpitation and near syncope 2 months before examination. The pre-test probability (PTP) score was 1% and baseline ECG showed typical features of WPW syndrome. Additionally, risk stratification was performed with EST using the Bruce protocol. Persistent ventricular preexcitation (VPE) with upsloping 3.0 mm ST-segment depression was found in precordial leads at the fourth stage, while the aVR lead showed a 3.0 mm ST-segment elevation. Conclusion:...

Post-infarction ventricular septal rupture; a case report: An insight to the AmericasCase reports

David Jacobo Sánchez Amaya, Nancy Gabriela Rodríguez Murillo, Daniel Sánchez Amaya, Haroldo López García

Cor Vasa 2024, 66(1):76-79 | DOI: 10.33678/cor.2023.065  

Ventricular septal rupture (VSR) constitutes one of the possible mechanical complications following an acute myocardial infarction (AMI), even though very infrequent, it bears an elevated high mortality rate. Although most patients develop florid clinical manifestations, a minority might have a silent evolution, experiencing a subacute heart failure (HF) onset or decompensation instead. Once identified, prompt treatment is mandatory. Management, consistent of medical therapy (i.e.; anti-ischemic and afterload reducing medications) along with definite repair, either through interventional or surgical technique, is necessary, since if uncor- rected,...

(Cardiac tumour presenting as fever of unknown origin)Case reports

Lenka Hartmanová, Juraj Hrečko, Monika Fialová, Karel Mědílek, Pavel Žáček, Václav Stejskal, Petr Pařízek

Cor Vasa 2024, 66(1):71-75 | DOI: 10.33678/cor.2023.073  

Cardiac myxoma is the most common primary tumour of the heart. We present a case of a 46-year-old man with a 3-month history of progressive fatigue, exertional dyspnoea, fever, and elevated inflammatory markers. Echocardiography revealed left atrial tumour. The patient underwent successful surgical resection of the tumour; the histological study of the mass confirmed the diagnosis of myxoma.

(The CD36 receptor - the link between inflammation, lipid metabolism, and cardiovascular disease)Review articles

Rudolf Poledne, Ivana Králová Lesná

Cor Vasa 2024, 66(1):66-70 | DOI: 10.33678/cor.2024.005  

The CD36/FAT (fatty acid translocator) receptor is a crucial player in cardiovascular diseases, featuring a consistent structure across species. Its expression in adipose tissue, skeletal muscle, liver, and arterial wall macrophages underscores its importance. Beyond scavenging oxidized LDL (oxLDL), CD36 accelerates the pro-inflammatory processes in all these organs. Specific microenvironments of adipose tissue with high concentrations of free long-chain fatty acids, insulin, and glucose induce polarization by tissue-specific path- ways producing metabolically activated pro-inflammatory macrophages (MAPIMs) with high CD36 expres- sion. The proportion...