Cor et Vasa - Latest articles
Results 31 to 60 of 347:
23. konference České asociace akutní kardiologieAbstracts
Hotel Thermal, Karlovy Vary, 30. 11.–2. 12. 2025
Cor Vasa 2025, 67(6) 
Loučíme se s MUDr.. Pavlem FormánkemPersonalities
Michael Aschermann
Cor Vasa 2025, 67(6)
Zemřel MUDr. Pavel FormánekPersonalities
Petr Neužil, Martin Mates
Cor Vasa 2025, 67(6)
Neuregulin-1 and Cardiovascular DiseasesReview articles
Lutfu Askin, Yahya Urkmez, Hakan Ozerol
Cor Vasa 2025, 67(6):751-757
Cardiac tissue expresses neuregulin-1 (NRG-1), a growth factor. NRG-1 may treat heart failure (HF), myocardial infarction, cardiomyopathy, and arrhythmias. NRG-1 improves angiogenesis, cardiomyocyte development, and cardiac fibrosis in HF. These effects increase left ventricular function and minimise cardiac events (CE). NRG-1 reduces myocardial infarct size and promotes tissue regeneration. Angiogenesis and reduced inflammation and fibrosis in the infarcted region by NRG-1 minimise the incidence of unfavourable CE. NRG-1 improves left ventricular function and cardiac fibrosis in cardiomyopathy. NRG-1 modulates ion channels and reduces cardiac inflammation...
(Liver steatosis as a risk of coronary heart disease)Review articles
Rudolf Poledne, Dita Pajuelo, Ivana Králová Lesná
Cor Vasa 2025, 67(6):745-749
The prevalence of steatosis in MASLD (metabolic dysfunction-associated steatotic disease) varies in different populations, up to 30%. Although steatosis might progress into steatohepatitis, cirrhosis and finally to the liver failure, it is not a necessary development very probably. Simple steatosis is a reversible status related to the total volume of ectopic fat in the body. Triglyceride (TG) accumulation in the liver is partly genetically determined, but it is also related to nutrition. High content of saturated fat in the hypercaloric diet leads to an increase in the content of fat droplets in the hepatocytes, whereas unsaturated fat has the opposite...
Kapesní verze doporučených postupů ESC. Doporučené postupy ESC pro léčbu kardiovaskulárních onemocnění v těhotenství - 2025Guidelines
De Backer J, Haugaa KH, Hasselberg NE, de Hosson M, Brida M, Castelletti S, Cauldwell M, Cerbai E, Crotti L, de Groot NMS, Estensen ME, Goossens ES, Haring B, Kurpas D, McEniery CM, Peters SAE, Rakisheva A, Sambola A, Schlager O, Schoenhoff FS, Simoncini T, Steinbach F, Sudano I, Swan L, Valente AM, De Backer J, Haugaa KH, Hasselberg NE, de Hosson M, Brida M, Castelletti S, Cauldwell M, Cerbai E, Crotti L, de Groot NMS, Estensen ME, Goossens ES, Haring B, Kurpas D, McEniery CM, Peters SAE, Rakisheva A, Sambola A, Schlager O, Schoenhoff FS, Simoncini T, Steinbach F, Sudano I, Swan L, Valente AM, Miloš Táborský, Renata Cífková, Aleš Linhart, Petra Vysočanová
Cor Vasa 2025, 67(6):709-744
Speckle Tracking Echocardiography Predicts Left Ventricular Remodeling after Acute ST-Segment Elevation Myocardial Infarction in Patients Undergoing Primary PCIOriginal research articles
Ahmed A. Elamragy, Irini Samuel, Ahmed Hassan, Reda Hussein Diab, Mohamed Abdel Ghany, Ahmed Mohsen
Cor Vasa 2025, 67(6):698-707
Purpose: Left ventricular remodeling (LVR) following ST-segment elevation myocardial infarction (STEMI) significantly impacts prognosis. Although three-dimensional echocardiography (3D-echo) accurately assesses LV volume, early LVR prediction remains challenging. This study evaluated whether baseline global longitudinal strain (GLS), a non-invasive echocardiographic marker, predicts LVR six months post-STEMI in patients treated with primary percutaneous coronary intervention (PPCI). Methods: This prospective observational study included 53 first-time STEMI patients who underwent PPCI and completed a six-month echocardiographic follow-up. LV function...
(Application of KDIGO guidelines for CKD diagnosis in clinical practice: cross-sectional study of eGFR and ACR testing in the Czech Republic)Original research articles
Ivo Hlaváč, Miloš Táborský, Matěj Opatrný
Cor Vasa 2025, 67(6):687-696
Background: Chronic kidney disease (CKD) affects 9-13% of the global population. KDIGO guidelines recommend simultaneous albumin-to-creatinine ratio (ACR) and estimated glomerular filtration rate (eGFR) testing for proper CKD staging. Data on compliance with these standards in Czech practice are lacking. Methods: Cross-sectional retrospective analysis of 62,567 patients examined between January 2022 and April 2025 in Unilabs laboratories. We assessed availability of eGFR and ACR testing across specialties and compliance with KDIGO recommendations. Results: Median age 67.0 years (IQR 54.3-75.4), 54% male. ACR was tested in 97.2% of patients, eGFR in...
Surgical Repair of Post-Infarction Ventricular Septal Rupture with or without Concomitant Coronary Artery Bypass Grafting: A Systematic Review and Meta-Analysis of Outcomes and Prognostic ImplicationsOriginal research articles
Ery Irawan, Yan Efrata Sembiring
Cor Vasa 2025, 67(6):677-685
Introduction: Post-myocardial infarction ventricular septal rupture (VSR) is a rare but fatal complication that requires urgent surgical repair. The benefit of adding concomitant coronary artery bypass grafting (CABG) remains controversial. While CABG may protect viable myocardium in patients with coronary artery disease, it also increases operative complexity and ischemic time. This review evaluates the prognostic impact of concomitant CABG during VSR repair. Methods: A systematic literature search was conducted in PubMed, ScienceDirect, BMC, and Springer databases according to PRISMA guidelines. Studies reporting surgical VSR repair with and without...
Determinants of Ineligibility for Intravenous Iron Therapy in Patients with Heart Failure and LVEF <45%: A Retrospective Cohort StudyOriginal research articles
Jozef Dodulík, Kristýna Podzemná, Klára Musiolová, Jiří Vrtal, Jiří Plášek, Jan Václavík
Cor Vasa 2025, 67(6):671-676
Background: Intravenous iron therapy improves symptoms and reduces hospitalizations in patients with heart failure (HF) and iron deficiency (ID). Clinical trials evaluating this therapy have often excluded patients with higher hemoglobin (HGB) levels, although current European Society of Cardiology guidelines do not specify an upper HGB limit. This study aimed to assess how HGB thresholds influence eligibility for intravenous iron among real-world HF patients with left ventricular ejection fraction (LVEF) < 45%. Methods: We retrospectively analyzed consecutive patients attending a specialized HF outpatient clinic in 2024. ID was defined as ferritin...
Libor Jelínek, Samuel Genzor, Jan Václavík a kolektiv: Adherence k medikaci kardiovaskulárních onemocnění v praxiBook reviews
Prof. MUDr. Jan Petrášek, DrSc.
Cor Vasa 2025, 67(5):664 | DOI: 10.33678/cor.2025.115
Jiří Vítovec, Monika Špinarová, Anna Chaloupka, Karel Lábr: Farmakoterapie srdečního selháníBook reviews
Prof. MUDr. Jan Petrášek, DrSc.
Cor Vasa 2025, 67(5):663 | DOI: 10.33678/cor.2025.111
Peter Baláž, Adam Whitley Cévní chirurgie do kapsy. Vascular Surgery: A Pocket GuideBook reviews
Prof. MUDr. Michael Aschermann, DrSc. FACC, FESC
Cor Vasa 2025, 67(5):662 | DOI: 10.33678/cor.2025.110
Mgr. Klára Procházková, odpovědná redaktorka Cor et Vasa, slaví životní jubileumPersonalia
Michael Aschermann
Cor Vasa 2025, 67(5):661 | DOI: 10.33678/cor.2025.109
Prof. MUDr. Eliška Sovová, Ph.D, MBA, slaví významné životní jubileumPersonalia
Michael Aschermann
Cor Vasa 2025, 67(5):659-660 | DOI: 10.33678/cor.2025.105
Memorandum o vzájemné spolupráciCurrent news
Prof. MUDr. Milan Macek jr., DrSc, MHA, Prof. MUDr. Petr Ošťádal, Ph.D., FESC, Prof. MUDr. Miloš Táborský, CSc., FESC, FACC, MBA, Prof. MUDr. Aleš Linhart, DrSc., FESC, FCMA, Doc. MUDr. Alice Krebsová, Ph.D.
Cor Vasa 2025, 67(5):655-657 | DOI: 10.33678/cor.2025.114
Abiotrophia defectiva - silent invader and real diagnostic challengeCase reports
Lujza Ondrušková, Marcela Tavačová, Tibor Malacký
Cor Vasa 2025, 67(5):651-654 | DOI: 10.33678/cor.2025.033
Abiotrophia defectiva belongs to the normal human microbiome of the oral cavity, gastrointestinal and urogenital tracts. Rarely, about 1-3% of all infective endocarditis, it can be the cause of infective endocarditis. Although uncommon, it is associated with high mortality and complication rates. The chronic course and difficult isolation requiring specialized culture media are contributing to a delayed diagnosis. Moreover, infective endocarditis by A. defectiva is known for its aggressive nature characterized by the development of large vegetations leading to massive, life-threatening systemic embolizations, valves destructions, and progressive...
Potential of pentoxifylline in preventing reperfusion injury after surgery on limb ischemia: a literature reviewReview articles
Abu Rizal Dwikatmono Johan, Danang Himawan Limanto, Heroe Soebroto
Cor Vasa 2025, 67(5):646-650 | DOI: 10.33678/cor.2025.032
Background: Acute limb ischemia (ALI) is characterized by a sudden loss of blood flow to the lower limbs, often resulting from embolism or thrombosis. Management of ALI is critical, as it can lead to severe complications, including ischemia-reperfusion injury (IRI) during revascularization procedures. IRI involves complex functional and structural changes following restoration of blood flow, leading to inflammation and oxidative stress. These pathological processes can exacerbate tissue damage and impede recovery. Pentoxifylline has emerged as a potential therapeutic agent due to its ability to improve blood flow and reduce the inflammatory response....
(Isolated dissection of the internal carotid artery)Review articles
Marek Hudák, Martin Koščo, Lucia Dekanová, Veronika Pavlíková, Mária Rašiová
Cor Vasa 2025, 67(5):631-640 | DOI: 10.33678/cor.2025.075
Isolated dissection of the internal carotid artery is a serious medical condition due to the risk of ischemic stroke developing, especially in young patients. Its management is complex, consisting of pharmacological and non-pharmacological, endovascular treatment. Each of the treatment options must be strictly indicated after meeting the strict indications. The aim of this article is to provide the reader with a comprehensive view of this disease from etiopathogenesis to treatment and prognosis. The most important goal is to provide the most up-to-date knowledge about the method of treatment and the indications of each treatment option.
(Non-Pharmacological Management of Ventricular Tachycardias in a Complex Cardiovascular Center)Review articles
Filip Schlosser, Petr Peichl, Josef Kautzner
Cor Vasa 2025, 67(5):620-630 | DOI: 10.33678/cor.2025.064
Ventricular arrhythmias significantly influence morbidity and mortality in patients with structural heart dis- ease. Implantable cardioverter-defibrillators positively affect survival but do not prevent ventricular arrhythmias. Until recently, the cornerstone of management of ventricular arrhythmias was administration of antiarrhythmic drugs, which have limited efficacy and non-negligible side effects. Nowadays, newer non-pharmacological treatment modalities have emerged, namely catheter ablation. Radiofrequency energy is considered the gold standard and its effect can be further augmented by using different types of catheters, alternative perfusion...
Short-term effects of exercise training program on patients with compensated chronic heart failureOriginal research articles
Omar El Tahan, Ghada Youssef, Yasser Baghdady, Mohamed Abdelghany, Ahmed Mohsen
Cor Vasa 2025, 67(5):601-612 | DOI: 10.33678/cor.2025.061
Background: About 1% to 2% of adults suffer from heart failure (HF), a complex syndrome with significant clinical and public health issues. Exercise training for heart failure seeks to enhance patients' physical fitness and quality of life while simultaneously diminishing the likelihood of hospitalizations and mortality. Poor heart failure patient participation was apparent despite strong guidelines for cardiac rehabilitation. Objectives: For evaluating how a brief, structured exercise training program impacts those suffering from compensated chronic heart failure in terms of improving clinical, laboratory, and echocardiographic parameters. Methods:...
Surgical Management and Postoperative Outcomes of Ventricular Septal Rupture Following Acute Myocardial Infarction: A Case SeriesOriginal research articles
Daud Yudhistira Sukanto, Yan Efrata Sembiring, Oky Revianto
Cor Vasa 2025, 67(5):597-600 | DOI: 10.33678/cor.2025.067
Introduction: Ventricular septal rupture (VSR) is a rare but life-threatening complication of acute myocardial infarction (AMI), occurring in approximately 0.2% of post-AMI cases. Surgical repair is the definitive treatment, it carries a high mortality risk, particularly when performed emergently. Aim: To present a case series of five patients with VSR following AMI and evaluate their surgical management and postoperative outcomes at Dr. Soetomo General Hospital Methods: A retrospective analysis was conducted on five male patients, aged 44 to 63 years, diagnosed with VSR post-AMI between 2023 and 2024. Patient demographics, VSR characteristics, surgical...
Cardiac sequelae after COVID-19: results of a one-year follow-up study with ECG monitoringOriginal research articles
Gabriela Matejová, Martin Radvan, Elis Bartečků, Veronika Bulková, Martin Kameník, Lumír Koc, Jana Hořínková, Radka Štěpánová, Petr Kala
Cor Vasa 2025, 67(5):591-596 | DOI: 10.33678/cor.2025.019
Objective: To evaluate the need for ECG monitoring of unselected patients recovered from COVID-19 and to estimate the risk of development of arrhythmias and heart rate variability change after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods: Between March 2020 and January 2021 patients who had recovered from PCR-proven SARS-CoV-2 symptomatic infection (alfa and beta variants) were enrolled in a prospective observational cohort study CoSuBr (COvid SUrvivals in BRno) and those with two 7-day ECG monitoring have been analysed. Demographic parameters, patient history, clinical evaluation, and 7-day ECG monitoring were recorded within...
(Minimally Invasive Mitral Valve Surgery via Video-Assisted Thoracotomy - A Single Center Study)Original research articles
Marián Homola, Štefan Lukačín, Tomáš Toporcer, Anton Bereš, Michal Trebišovský, Peter Šafár, Adrián Kolesár
Cor Vasa 2025, 67(5):586-589 | DOI: 10.33678/cor.2025.039
Minimally invasive mitral valve surgery (MIMVS), using video-assisted thoracoscopic surgery (VATS), has estab- lished itself as an effective approach in cardiac surgery over the past 30 years. This type of surgery allows for smaller incisions, leading to faster recovery and fewer postoperative complications. This retrospective study analyzed 54 patients who underwent minimally invasive mitral valve surgery between May 2018 and May 2024 at the Department of Heart Surgery, East Slovak Institute for Cardiovascular Diseases. The results showed that 92% of patients underwent mitral valve repair with the implantation of an annuloplasty ring, while in 8%...
Adherence to treatment in the elderly with chronic heart failureOriginal research articles
Lucie Karlická, Darja Jarošová
Cor Vasa 2025, 67(5):577-585 | DOI: 10.33678/cor.2025.035
Objective: The objective of this study was to investigate and evaluate adherence to treatment in the elderly with chronic heart failure and the significance of factors explaining it. Methods: This is cross-sectional correlational and descriptive quantitative study. The research sample consisted of 127 elderly people with chronic heart failure who met the specified criteria. To assess adherence to treatment in the elderly with chronic heart failure, the Czech version of the modified standardized questionnaire ACDI - Adherence of Patients with Chronic Disease Instrument was used. Data collection took place between 2023 and 2024 at the Cardiovascular...
Prophylactic Negative Pressure Therapy in Reducing the Risk of Sternal Wound Infection after Cardiac SurgeryOriginal research articles
Salifu Timbilla, Ján Gofus, Petr Smolák, Eva Čermáková, Jiří Manďák, Jan Vojáček
Cor Vasa 2025, 67(5):571-575 | DOI: 10.33678/cor.2025.030
Background: Postoperative sternal wound infections and dehiscence are serious complications of cardiac surgery that increase the length of hospital stay and healthcare costs. Standard wound care may be insufficient for preventing these complications in high-risk patients. Methods: We conducted a prospective, randomized study comparing the efficacy of closed incisional negative pressure wound therapy (ciNPWT) using Prevena (study group) versus standard wound dressing (control group) in patients at high risk of sternal wound infections following cardiac surgery. Primary outcomes included the incidence of sternal wound infection at seven days and three...
Endocardial radiofrequency ablation of septal hypertrophy in the interventional treatment of the hypertrophic obstructive cardiomyopathy; comparison with the alcohol septal ablation, pilot data of the randomized trialOriginal research articles
Katarína Doležalová, Zdeněk Stárek, Martin Pešl, Filip Souček, Jan Sitar, Tomáš Honěk, Jan Krejčí
Cor Vasa 2025, 67(5):561-570 | DOI: 10.33678/cor.2025.101
Introduction: Hypertrophic obstructive cardiomyopathy (HOCM) is characterized by dynamic left ventricular outflow tract (LVOT) obstruction due to asymmetric septal hypertrophy and systolic anterior motion (SAM) of the mitral valve. In patients with persistent symptoms despite optimized medical therapy, septal reduction therapy is indicated. While alcohol septal ablation (ASA) is a well-established catheter-based treatment, endocardial radiofrequency ablation of septal hypertrophy (ERASH) has recently emerged as a promising alternative. Aim of our study is to report the pilot data of the randomized study comparing efficacy and safety of ERASH versus...
Cardiovascular Risk Factors and DXA-Assessed Body Composition Changes after Laparoscopic Sleeve Gastrectomy: A One-Year Retrospective StudyOriginal research articles
Matej Pekař, Pavol Holéczy, Jitka Macháčková, Aleš Foltys, Zdeněk Švagera, Marek Bužga
Cor Vasa 2025, 67(5):555-560 | DOI: 10.33678/cor.2025.020
Background: While laparoscopic sleeve gastrectomy (LSG) is known to reduce weight, its impact on cardiovascular risk profile through changes in body composition remains unclear. Methods: This retrospective study evaluated 98 patients who underwent LSG, analyzing body composition via dual-energy X-ray absorptiometry (DXA) and cardiovascular risk parameters at baseline and 12 months post-surgery. Changes in weight, fat mass, lean mass, atherogenic lipid profile, and glucose metabolism were assessed, along with their interrelationships. Results: Significant reductions were observed in total body weight, fat mass, and lean mass at 12 months post-surgery...
The LACE Index: A Predictor of Mortality and Readmission in Cardiovascular DiseasesReview articles
Lutfu Askin, Yahya Urkmez, Okan Tanriverdi
Cor Vasa 2025, 67(5):641-645 | DOI: 10.33678/cor.2025.016
The LACE index is a predictive tool used in healthcare to estimate the risk of hospital readmission for patients who have been discharged from the hospital. LACE stands for length of stay, acuity of admission, comorbidity burden, and emergency department (ED) visits. It is a simple scoring system that assigns points to each of these four factors based on their presence and severity and then sums up the points to calculate the LACE index score. The LACE index is often used by healthcare providers to identify patients who may be at higher risk of being readmitted to the hospital after discharge. By identifying patients with higher LACE scores, healthcare...
Association of insertion/deletion (I/D) polymorphism of angiotensin-converting enzyme gene (ACE) with ST segment elevation myocardial infarction and factors risk in Western Algeria: case-control studyOriginal research articles
Asma Amrani-Midoun, Nadia Laredj, Taki Djebaili, Djelti Mounia, Abdelkader Djelloul, Lilia Zouli, Hamid Aoumeur, Nachi Mourad
Cor Vasa 2025, 67(5):614-619 | DOI: 10.33678/cor.2025.027
Background: Cardiovascular diseases are the leading cause of mortality worldwide. Acute coronary syndrome (ACS) is a multifactorial disease resulting from the interaction of environmental and genetic factors. The I/D polymorphism of the ACE gene has been associated with the risk of developing acute coronary syndrome (ACS). Our case-control study aimed to access the potential association of insertion/deletion (I/D) ACE (angiotensin converting enzyme) gene polymorphism and ST segment elevation myocardial infarction (STEMI) among a sample of Algerian patients from Western Algeria. Methods: We conducted a case-control study comprising 169...